Recombinant antibodies (RAbs) are monoclonal antibodies which are generated in vitro using synthetic genes.Recombinant antibodies over power the hurdles of conventional antibody by providing unlimited source of antibodies. Recombinant antibodies can be produced as full IgG expressed in mammalian cell lines or fab, scfv or VHH in E.Coli making it a cost effective way to the production of antibody. Conventional hybridomas tend to loose the antibody production capability by loosing the gene at any time point but recombinant antibody are reproducible reagent.