Hybridoma technology steps are a series of entrenched methods to produce mAbs ( monoclonal antibodies) to antigens of interest. Hybridoma cell lines are formed by combining a short-lived antibody-producing B cell and an immortal myeloma cell. Every hybridoma constitutively conveys a considerable[…]
Read MoreWhat is purified protein? Protein purification is necessary to identify the structures and functions before the study. It involves many steps, from disrupting the cells and isolating the proteins to removing impurities. If you require the protein purification process, you have samples[…]
Read MoreThe present situation demonstrated that many ill patients tend to have a high concentration of proinflammatory Cytokines, like interleukin-6, differentiated to moderately sick ones. The high level of cytokines indicates a prognosis in coronavirus. We summarise the clinical and pathologic aspects of[…]
Read MoreRecently, FDA (Food and Drug Administration) has enlarged the potential application of mAb (monoclonal antibody) therapy for inhibitory use, which are at serious risk due to a confirmed exposure to the virus. The permission was based on a substantial clinical trial that[…]
Read MoreTransmembrane TNF-α, a forerunner of the dissolvable form of TNF-α, is conveyed on activated macrophages, lymphocytes, and other cell types. So after processing by TFN-α-converting enzyme, the dissolvable form of TNF-α spilt from transmembrane TNF-α and mediated its biological activity through tiding[…]
Read MoreRecombinant proteins are coded by the manipulated gene of interest, with the recombinant protein generation specific to the protein expression. The recombinant gene combines the new genes with different gene segments of other species. Recombinant protein can be produced in large amounts[…]
Read MoreAntibodies, the Y shaped proteins, aka immunoglobulins (Igs), are produced by the plasma cells. These can identify the antigens that are foreign invaders or molecules as pathogens, toxins, and more. The Y shaped structure in the antibody is to locate and bind[…]
Read MoreB-cell And T-Cell Epitope Mapping With the antigen encounter, the host humoral immunity activates, which triggers the production of antibodies that are against the foreign invader protein epitopes. Immune system components recognise the epitope as antibodies, B cells and T cells. These[…]
Read MoreCancer has it all captured right from the ancient animals to the sufficient wildlife and humans. There are much fewer known cancers that affect the wildlife, yet there has been proven research that allows one to study and know from. The cancer animals sector[…]
Read MoreAnimals are cute creatures and add up a bulk amount of joy in the life of human beings. But, they also carry the potential to make us sick. Several diseases can be transmitted through animals, and these conditions are the zoonotic infection that we’re[…]
Read More