Understanding the immune memory and tracking variant immunity to the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is vital for improving the continuous diagnosis and enhancing treatment in form of vaccines for any future outbreaks. Monitoring the variant immunity for SARS-CoV-2 spike[…]
Read MoreThe very first monoclonal antibody approved by the U.S. FDA (Food and Drug Administration) in 1997 ushered a new era in therapeutic applications for patients. A clinical breakthrough was acknowledged in the 1990s when there was the successful development of a humanized[…]
Read MoreTreatment of diseases arose with the concept of antibodies back in the 1890s, by Emil Adolf von Behring. In the further 1960s, there were structural characteristics describers, forward marking discovery of production methods of Monoclonal Antibodies (mAbs). The first mAb, muromonab-CD3, was[…]
Read MoreGolimumab has been principally targeting and neutralizing TNF proving itself as a valuable human anti-tumor necrosis factor (TNF) monoclonal antibody, actively preventing inflammation and destruction of cartilage and bone. Golimumab, monoclonal antibody production, is largely represented by the biological community. 1. Sequential[…]
Read More