Blogs
SARS-CoV-2 Neutralizing Antibody Response Dynamics: Methods
The COVID-19 Pandemic has caused a lot of commotion globally, and with SARS-COV-2 Spike Protein causing it, there has been a surge for over a year...
Similarities Between Chimeric And Humanized Antibodies
Chimeric And Humanized Antibodies are monoclonal antibodies that are non-human and are set into production by mice or rodents under specific...
Recombinant antibodies’ role in medical research and development
The definitive monoclonal antibody (mAb) production procedure involves fusing myeloma cells with desired antibody-producing splenocytes to produce...
Researchers create an antibody test to monitor SARS-CoV-2 variant immunity
Understanding the immune memory and tracking variant immunity to the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is vital for...
The Role of TNF Alpha Antibodies in Treating Inflammatory Disorders
Inflammatory disorders, such as rheumatoid arthritis (RA), Crohn’s disease, and psoriasis, are characterized by chronic inflammation that can lead...
Production of Monoclonal Antibodies
The definitive monoclonal antibody (mAb) production procedure involves fusing myeloma cells with desired antibody-producing splenocytes to produce...
Primary And Secondary Antibodies: How They Differ?
Antibodies, the Y shaped proteins, aka immunoglobulins (Igs), are produced by the plasma cells. These can identify the antigens that are foreign...
Pro-Inflammatory Cytokines
Pro-Inflammatory Cytokines are defined terms for the immunoregulatory cytokines that side with inflammation. The highlight effect is the balance...
The Impact of Drug-Resistant Mycobacterium Tuberculosis Strains
Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis (M. tuberculosis), remains one of the deadliest infectious diseases worldwide....
Phage Display- A Powerful Technique For Immunotherapy
Phages are viruses that infect bacteria specifically and create more phage proteins resulting in more phage particles. These phages carry immense...
Phage Display Libraries For Therapeutic Antibody Discovery
Phage display antibody library technology has played an important role in the remarkable progress of discovering and optimizing antibodies for...
The Role of CD32 Protein in Disease Pathogenesis and Treatment
The immune system is an intricate network of cells and proteins that protects the body from infections and diseases. Among the key players in this...
Peptide Phage Display Technology In Biomedical Science – Advancement And Applications
B-cell And T-Cell Epitope Mapping With the antigen encounter, the host humoral immunity activates, which triggers the production of antibodies that...
One Health: A Brief Introduction
For decades, tens to thousands of people get sick from the diseases that are spread between humans and animals each year. The disorders like rabies...
Know The Medical Uses For Biologics Drugs
Biologics, aka biologic drugs, are any medical therapy methods opted from living beings as humans, microorganisms, and animals. Biologic drugs are...
Nine Biopharma Trends to Watch in 2024
Biomedical breakthroughs in recent years have been revolutionary, and they are likely to cause substantial industry upheavals shortly, drawing new...
The Role of AI and Machine Learning in Biopharma Drug Discovery
In recent years, artificial intelligence (AI) and machine learning (ML) have emerged as transformative tools in the field of biopharma drug...
Overcoming Common Challenges in Antibody Drug Discovery
Antibody drug discovery is a pivotal area of research in the biopharmaceutical industry, with therapeutic antibodies being used to treat a wide...
Applications of Antibody Discovery in Cancer Therapy and Beyond
Antibody discovery has revolutionized the field of medicine, particularly in cancer therapy. These powerful biomolecules are now integral to various...
Can IL-6R Antibodies Help Combat Severe Infections and Inflammation?
Inflammation is a crucial immune response to infection, injury, or disease. However, when inflammation becomes excessive or uncontrolled, it can...
The Future of Therapeutic Antibodies: Innovations and Emerging Trends
Therapeutic antibodies have transformed modern medicine, offering targeted treatments for a range of diseases, from cancer to autoimmune disorders....
Environmental Factors Affecting Recombinant Protein Expression in E.coli
The expression of recombinant proteins in Escherichia coli (E. coli) has become a cornerstone of biotechnology and pharmaceutical development. This...
India’s indigenous solution to COVID-19 in progress
NAGPUR, India, Nov. 19, 2020 /PRNewswire/ — To fight the Novel coronavirus SARS-COV-2, the virus behind the worldwide outbreak of COVID-19...
Introduction To Recombinant Proteins & Its Applications
What Are Recombinant Proteins? The proteins that are formed into a host by transfecting foreign genes into them are recombinant proteins....
How Does Monoclonal Antibody Therapy Work?
Recently, FDA (Food and Drug Administration) has enlarged the potential application of mAb (Monoclonal Antibody) therapy for inhibitory use, which...
Immune Evasion And Provocation By Mycobacterium tuberculosis
Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humankind for millennia. M. tuberculosis has been prevalent to...
Interleukin-10: Exploring the Anti-Inflammatory Properties of This Crucial Cytokine
Cytokines are vital signalling molecules in the immune system, orchestrating various immune responses and maintaining homeostasis. Interleukin-10...
Expression & Purification of Histidine Tag and Tagless TNF alpha- Recombinant Protein
Tumor necrosis factor α (TNFα) is a pyrogen cytokine released from immune cells in the acute phase of inflammation and infection. TNF-alpha shows...
Cytokines, major role in COVID-19 Prognosis
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for an ongoing pandemic that has killed over 4,75,00 people globally...
Cytokine Storm in COVID-19
The present situation demonstrated that many ill patients tend to have a high concentration of proinflammatory Cytokines, like interleukin-6,...
What to Anticipate from Monoclonal Antibody Therapy Administration
Monoclonal antibody (mAb) therapy has revolutionized modern medicine, providing highly targeted treatments for various conditions, including cancer,...
What is the role of TNF alpha in autoimmune disease 02 Sep Share
Autoimmune diseases are complex disorders where the immune system mistakenly attacks the body’s own tissues. Among the numerous cytokines involved...
New Approaches in Diagnosing Mycobacterium Tuberculosis Infections
Mycobacterium tuberculosis (M. tuberculosis), the bacterium responsible for tuberculosis (TB), remains a global health challenge, affecting millions...
Clinical Trials and Therapeutic Antibodies: What’s New?
The evolution of therapeutic antibodies has marked a pivotal shift in the landscape of modern medicine. From life-saving cancer therapies to...
Recent Breakthroughs in Antibody Discovery and Application
Antibody-based therapies have become a cornerstone in modern medicine, transforming the way we treat diseases such as cancer, autoimmune disorders,...
How Cytokines Affect Immune Responses in Drug Development
In the complex landscape of immunology, cytokines stand as pivotal regulators of immune responses. These small proteins play crucial roles in...
Advantages of Recombinant Protein Expression in E. coli
Recombinant protein expression is a cornerstone of modern biotechnology, enabling the production of proteins for research, therapeutic, and...
The Growing Importance of Therapeutic Antibodies in Modern Medicine
The Growing Importance of Therapeutic Antibodies in Modern Medicine In the evolving landscape of modern medicine, therapeutic antibodies have...
Interleukins and Their Impact on Immune System Regulation
Interleukins, a group of cytokines, are essential messengers in the immune system, playing a pivotal role in regulating immune responses,...
Applications and Benefits of IL-6 R Antibodies
In the ever-evolving landscape of biotechnology and therapeutic development, antibodies are pivotal in addressing a wide array of medical...
Optimizing Antibody Development: The Role of Hyper Immune Libraries
Optimizing Antibody Development: The Role of Hyper Immune Libraries Land of biotechnology and therapeutic development, antibodies play a significant...
The Ethical Considerations of Monoclonal Antibody Use in India
Monoclonal antibodies (mAbs) are a cornerstone of modern medical therapies, playing important roles in treating cancers, autoimmune diseases, and...
Antibody Drug Discovery: How Can You Get Involved in this Exciting Field
The field of antibody drug discovery is one of the most dynamic and rapidly advancing areas in biomedical research. Antibodies, with their high...
Anti-TNF Therapy: Past, Present, And Future
While therapeutics have been regarded as a prominent field, small molecules have dominated the field. Development of a plethora of vital medicines...
Steps Involved in Hybridoma Technology
Hybridoma technology steps are a series of entrenched methods to produce mAbs (monoclonal antibodies) to antigens of interest. Hybridoma cell lines...
Effective Methods For Purifying Protein
Recently, FDA (Food and Drug Administration) has enlarged the potential application of mAb (Monoclonal Antibody) therapy for inhibitory use, which...
Engineering High-Affinity Antibodies: Sharpening the Tools for Research and Therapeutics
In the rapidly advancing fields of biotechnology and medicine, the development of high-affinity antibodies is a cornerstone for both research and...
A Powerful Technique: Generation and Characterization of Chimeric Antibodies
Chimeric antibody, a hybrid molecule that combines the variable regions of one species, typically mice, with the constant regions of another...
The Future of CD32 Protein-Based Therapies
CD32, also known as FcγRII, is a low-affinity receptor for the Fc region of immunoglobulin G (IgG). It plays a critical role in the immune system by...
What are the applications of therapeutic antibodies?
Therapeutic antibodies have emerged as a transformative class of biopharmaceuticals, revolutionizing the treatment of various diseases. These...
How are recombinant proteins expressed using bacterial vectors?
The expression of recombinant proteins using bacterial animal and plant vectors has become a cornerstone of biotechnology, allowing for the...
Antibody Drug Discovery: A Cost Effective Approach To Drug Development
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
How do Therapeutic Antibodies Work: A Deep Dive Into Their Mechanism Of Action
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
TNF-alpha Antibodies: A Beacon of Hope for Patients with Chronic Inflammatory Conditions
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
Optimizing Hybridoma Technology for Enhanced Antibody Production
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
Choosing the Right Protein Purification Method for Your Needs
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
The Process of Phage Display Antibody Library Selection
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
The Role of CD32 Protein in Antibody-Dependent Cellular Cytotoxicity
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
What Is Protein Purification? Definition, Methods, & More
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
What is the role of TNF alpha in autoimmune disease
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
Therapeutic Antibodies Explained: A Simple Guide for Patients
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
The Future of Infectious Disease Treatment: Can Monoclonal Antibodies Be the Answer?
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
Unlocking thе Potеntial: Rеcombinant Protеin Tеchnology in Rеsеarch Rеvolution
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
Exploring the Global Reach of TNF Alpha Neutralizing Antibodies
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
Explore the Diverse Uses of Recombinant Proteins?
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
The Power Of Therapeutic Antibodies: How They Work and Their Potential Benefits
Antibodies, the Y shaped proteins, aka immunoglobulins (Igs), are produced by the plasma cells. These can identify the antigens that are foreign...
Beyond Traditional Treatments: How Recombinant Human Proteins Are Revolutionizing Healthcare
Phages are viruses that infect bacteria specifically and create more phage proteins resulting in more phage particles. These phages carry immense...
Taming the Immune Response: Strategies for Optimizing Antibody Libraries
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
The Intricate Web of Immunity: How Proteins Orchestrate the Body’s Defense
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
Unlocking The Potential Of Your Immune System: The Role Of Engineered Antibodies
The use of recombinant proteins has emerged at a greater level in the present scenario as they provide several health benefits and are being used...
Transforming Healthcare in India The Impact of Monoclonal Antibodies as a Beacon of Hope for Millions
Introduction: The Indian healthcare sector has undergone a groundbreaking metamorphosis in recent years with revolutionary advancements which...
A Regenerative Revolution: Biopharma’s Pioneering Efforts in Tissue Repair and Recovery
Introduction In a fast-paced and continually developing healthcare area, regenerative medicine arises as the ray of sunlight that sheds light on...
Engineered Antibodies: Destroying Disease for Precise Treatment
Introduction: However, the field of medical science is a dynamic one and solutions geared towards finding better treatments that are more directed...
STAT 3: EYE CATCHER FOR DRUG RESISTANCE CANCER THERAPEUTICS
Signal Transducer and Activator of Transcription STAT proteins are intracellular transcription factors that mediate many aspects: Cellular immunity...
The Journey Of Antibody: From The Magic Bullet To Bedside Drug
All through three-generation, we have witnessed the wonderful use of Monoclonal antibody production in the way it helps in our diagnosis and...
The Easiest-to-Understand: Overview of Protein Expression
In protein research, the term may apply to either the object of study or the laboratory technique required to manufacture protein. The latter...
Types of Antibody Engineering Services
At GeNext Genomics, we are highly proud to serve the industry with the ability to cater for clients with antibody engineering services. These...
The Multifaceted Roles of STAT3 in Heart Disease and Triple Negative Breast Cancer
Overview of STAT3: 1. Heart: Signal Transducer and Activator of Transcription 3 (STAT3), a signaling molecule and transcription factor has an...
Therapeutic Monoclonal Antibodies And Its Increasing Importance In The Healthcare
Treatment of diseases arose with the concept of antibodies back in the 1890s, by Emil Adolf von Behring. In the further 1960s, there were structural...
Use Of Monoclonal Antibody In Cancer Treatment
What Are Monoclonal Antibodies (MABs)? Monoclonal antibodies are proteins produced in the laboratory that can bind to body cells, even cancer cells....
Use of Recombinant Protein in Veterinary Medicine
The industry experts have it brewing that recombinant proteins have an elegant potential for the use of veterinary vaccines and can stand as a major...
Use Of Golimumab In The Treatment Of Rheumatoid Arthritis, Psoriatic Arthritis, Or Ankylosing Spondylitis
Golimumab has been principally targeting and neutralizing TNF proving itself as a valuable human anti-tumor necrosis factor (TNF) monoclonal...
What Role Do Inflammatory Cytokines Play in Cancer Cachexia
A tumor affects the body beyond its site of action, and one such effect is known as cancer cachexia. The cause of cancer cachexia is systemic...
What Is Recombinant Protein Expression?
Recombinant proteins are coded by the manipulated gene of interest, with the recombinant protein generation specific to the protein expression. The...
5 Stages of Biopharma Drug Discovery
Biopharma Drug Discovery is hitting right at the market spaces and seems to have a massive impact on drug development. These are broken down as...
4 Tips For Monoclonal Antibody Production
Monoclonal Antibody Production is an important part of the research, diagnostics, product, and development that provides several benefits to...
A Drug Delivery System for Administration of Anti–TNF-α Antibody
An Antibody Engineering Service against tumor necrosis factor-alpha (TNF-α), like infliximab, is an attractive therapeutic approach to treat ocular...
A Quick Guide To IL6 Protein (Interleukin 6)
What is Interleukin 6? Interleukin 6 or IL6 is a protein, a member of the IL-6 Family with polypeptide cytokines and four alpha-helix structures....
Advantage of Using Monoclonal over polyclonal Antibody
Antibodies are giant Y-shaped proteins known as immunoglobulins produced by B cells as a part of the flexible human response when encountering a...
A Time and Cost-Effective Consistent Protein Production Platform
RESEARCH-GNG: Prashant Thakre, Chinmay Umbarkar, Komal Talreja, Sidhant Vyas, Jawad Baksh, Kalyani Dange, Akash Nehare, Vilas Danav, Ashwin...
The Future of Biotechnology: Recombinant Protein Production
In the dynamic field of biotechnology, recombinant protein production has been a game-changer, revolutionizing our ability to create a wide range of...
Phage Display Libraries for the Development and Discovery of Therapeutic Antibodies
Antibody Library, Phage Display Antibody Library Antibodies are an essential component of our immune system, playing a crucial role in identifying...
A choice between Monoclonal and Polyclonal Antibodies: Scientist Perspective
In immunology and medical research, antibodies are critical in detecting and neutralizing harmful pathogens. Our immune system produces these...
Biological Activities of Transmembrane TNF-α as a Ligand
Transmembrane TNF-α, a forerunner of the dissolvable form of TNF-α, is conveyed on activated macrophages, lymphocytes, and other cell types. So...
Bispecific antibodies’ evolution
The very first monoclonal antibody approved by the U.S. FDA (Food and Drug Administration) in 1997 ushered a new era in therapeutic applications for...
Cancer In Animals And Humans
Cancer has it all captured right from the ancient animals to the sufficient wildlife and humans. There are much fewer known cancers that affect the...
Challenges In The Development of Therapeutic Antibody
The progress in engineering and clinical development has been remarkable in the development of Therapeutic Antibody for 40 years, with the work done...
Common Zoonotic Diseases Found In Both Humans & Animals
Animals are cute creatures and add up a bulk amount of joy in the life of human beings. But, they also carry the potential to make us sick. Several...
Antibody Engineering Services: An Overview
Antibodies are an essential immune system component B-cells produce to neutralize pathogens such as bacteria, viruses, and toxins. With the...
Scope of Monoclonal Antibody Drugs
Introduction Monoclonal Antibody Drugs are a type of biological therapy that has revolutionized the treatment of several diseases, including cancer,...